Curation Details
Interaction ID: IM-11129-2

Unique identifier for interactor Auniprotkb:P61586
Unique identifier for interactor Buniprotkb:Q969H4
Alternative identifier for interactor Aintact:EBI-446668
uniprotkb:P06749
uniprotkb:Q5U024
uniprotkb:Q9UEJ4
uniprotkb:Q53HM4
uniprotkb:Q9UDJ0
ensembl:ENSP00000400175.1
ensembl:ENSP00000408402.3
ensembl:ENSP00000503282.1
ensembl:ENSP00000504180.1
Alternative identifier for interactor Bintact:EBI-741671
uniprotkb:O95381
uniprotkb:B1AMW9
ensembl:ENSP00000363371.5
Aliases for Apsi-mi:rhoa_human(display_long)
uniprotkb:Rho cDNA clone 12(gene name synonym)
uniprotkb:ARHA(gene name synonym)
uniprotkb:RHO12(gene name synonym)
uniprotkb:RHOA(gene name)
psi-mi:RHOA(display_short)
uniprotkb:ARH12(gene name synonym)
Aliases for Bpsi-mi:cnkr1_human(display_long)
uniprotkb:CNK homolog protein 1(gene name synonym)
uniprotkb:Connector enhancer of KSR-like(gene name synonym)
uniprotkb:CNKSR1(gene name)
psi-mi:CNKSR1(display_short)
uniprotkb:CNK1(gene name synonym)
Interaction detection methodspsi-mi:"MI:0012"(bioluminescence resonance energy transfer)
First authorLopez-Ilasaca et al. (2005)
Identifier of the publicationpubmed:15670823
mint:MINT-5217486
imex:IM-11129
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:2364"(proximity)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-1244009
imex:IM-11129-2
Confidence scoreintact-miscore:0.47
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:1B, 2B, 3A Supp 3
comment:Gly14val RhoA is constitutively active.
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human-293)
taxid:9606(Homo sapiens HEK293 embryonic kidney cell)
Parameters of the interaction-
Creation date2005/03/08
Update date2024/11/28
negative Boolean valuefalse
Feature(s) for interactor Atag:?-?
mutation increasing interaction:14-14
Feature(s) for interactor Bgreen fluorescent protein tag:?-?
sufficient binding region:384-504(IPR001849)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BPredetermined participant