Curation Details
Interaction ID: IM-10914-1

Unique identifier for interactor Auniprotkb:P08238
Unique identifier for interactor Buniprotkb:P08107
Alternative identifier for interactor Aintact:EBI-352572
uniprotkb:Q5T9W7
uniprotkb:Q9NQW0
uniprotkb:Q9NTK6
uniprotkb:B2R5P0
ensembl:ENSP00000325875.3
ensembl:ENSP00000360609.1
ensembl:ENSP00000360709.5
ensembl:ENSP00000481908.1
intact:EBI-26518782
Alternative identifier for interactor Bintact:EBI-629985
uniprotkb:P19790
uniprotkb:Q5JQI4
uniprotkb:Q5SP17
uniprotkb:Q9UQL9
uniprotkb:Q9UQM0
intact:EBI-4404728
uniprotkb:B4E3B6
Aliases for Apsi-mi:hs90b_human(display_long)
uniprotkb:HSP90AB1(gene name)
psi-mi:HSP90AB1(display_short)
uniprotkb:HSP90B(gene name synonym)
uniprotkb:HSPC2(gene name synonym)
uniprotkb:HSPCB(gene name synonym)
uniprotkb:Heat shock 84 kDa(gene name synonym)
uniprotkb:HSPC3(gene name synonym)
uniprotkb:Heat shock protein family C member 3(gene name synonym)
Aliases for Bpsi-mi:hsp71_human(display_long)
uniprotkb:HSPA1A(gene name)
psi-mi:HSPA1A(display_short)
uniprotkb:HSPA1(gene name synonym)
uniprotkb:HSPA1B(gene name)
psi-mi:HSPA1B(display_short)
uniprotkb:Heat shock 70 kDa protein 1/2(gene name synonym)
uniprotkb:HSX70(gene name synonym)
Interaction detection methodspsi-mi:"MI:0006"(anti bait coimmunoprecipitation)
First authorFalsone et al. (2005)
Identifier of the publicationpubmed:16263121
imex:IM-10914
mint:MINT-5218047
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0914"(association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-709762
imex:IM-10914-1
Confidence scoreintact-miscore:0.35
Complex expansionpsi-mi:"MI:1060"(spoke expansion)
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactioncaution:The AC68 antibody is specific for both hsp90 alpha and beta which may have the same interactors. Only Hsp90 beta was identified.
dataset:Synapse - Interactions of proteins with an established role in the presynapse.
dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human-293)
taxid:9606(Homo sapiens HEK293 embryonic kidney cell)
Parameters of the interaction-
Creation date2005/11/15
Update date2024/09/10
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APeptide massfingerprinting
Participant identification method for interactor BPeptide massfingerprinting