Unique identifier for interactor A | uniprotkb:P54252 |
Unique identifier for interactor B | uniprotkb:P55072 |
Alternative identifier for interactor A | intact:EBI-946046 uniprotkb:A7LFZ5 uniprotkb:D6RDL9 uniprotkb:E9PB63 ensembl:ENSP00000496695.1 uniprotkb:O15284 uniprotkb:O15285 uniprotkb:O15286 uniprotkb:Q8N189 uniprotkb:Q96TC3 uniprotkb:Q96TC4 uniprotkb:Q9H3N0 |
Alternative identifier for interactor B | intact:EBI-355164 uniprotkb:Q9UCD5 uniprotkb:B2R5T8 uniprotkb:Q0V924 uniprotkb:Q2TAI5 intact:EBI-1046421 ensembl:ENSP00000351777.6 uniprotkb:Q969G7 intact:EBI-10175326 uniprotkb:V9HW80 |
Aliases for A | psi-mi:atx3_human(display_long) uniprotkb:ATXN3(gene name) psi-mi:ATXN3(display_short) uniprotkb:ATX3(gene name synonym) uniprotkb:MJD(gene name synonym) uniprotkb:MJD1(gene name synonym) uniprotkb:SCA3(gene name synonym) uniprotkb:Machado-Joseph disease protein 1(gene name synonym) uniprotkb:Spinocerebellar ataxia type 3 protein(gene name synonym) |
Aliases for B | psi-mi:tera_human(display_long) uniprotkb:VCP(gene name) psi-mi:VCP(display_short) uniprotkb:HEL-220(gene name synonym) uniprotkb:HEL-S-70(gene name synonym) uniprotkb:"15S Mg(2+)-ATPase p97 subunit"(gene name synonym) uniprotkb:Valosin-containing protein(gene name synonym) |
Interaction detection methods | psi-mi:"MI:0006"(anti bait coimmunoprecipitation) |
First author | Boeddrich et al. (2006) |
Identifier of the publication | pubmed:16525503 mint:MINT-5218414 imex:IM-10821 |
NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
Interaction types | psi-mi:"MI:0915"(physical association) |
Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
Interaction identifier(s) in the corresponding source database | intact:EBI-1784626 imex:IM-10821-5 |
Confidence score | intact-miscore:0.68 |
Complex expansion | - |
Biological role A | Unspecified role |
Biological role B | Unspecified role |
Experimental role A | Bait |
Experimental role B | Prey |
Interactor type A | Protein |
Interactor type B | Protein |
Annotations for the interaction | figure legend:2A delivery method:P54252; P55072 transfection comment:The insertion of Gln residues due to CAG repeat expansion in SCA3 patients results in three fold increased binding to VCP. full coverage:Only protein-protein interactions curation depth:imex curation |
NCBI Taxonomy identifier for the host organism | taxid:9534(chlae-cos_1) taxid:9534(Chlorocebus aethiops COS-1 cells) |
Parameters of the interaction | - |
Creation date | 2006/07/26 |
Update date | 2018/01/19 |
negative Boolean value | false |
Feature(s) for interactor A | mutation increasing interaction strength:296..296-305..305 |
Feature(s) for interactor B | flag tag:?-? |
Stoichiometry for interactor A | - |
Stoichiometry for interactor B | - |
Participant identification method for interactor A | Anti tag western blot |
Participant identification method for interactor B | Anti tag western blot |